5817 : Lupus Anticoagulant Screen

INFORMATION:

Alternate Name:

Lupus Inhibitor Screen

Methodology:

Clot Detection

Clinical Utility:

Used to detect lupus anticoagulant (LA) in the blood. LA is an autoantibody associated with excess blood clot formation. Several types of inhibitors cause PTT prolongation. One of the main causes is the so-called "lupus anticoagulant" which is one of the many antibodies in the Antiphospholipid Antibody Syndrome. Patients with a lupus anticoagulant have an increased risk of both arterial and venous thrombosis (abnormal clotting); thus, the term 'lupus anticoagulant' is a misnomer (called an anticoagulant because it paradoxically causes a prolonged PTT). The lupus anticoagulant can be associated with the disease known as systemic lupus erythrematosis (SLE or "Lupus"), hence its name. This test checks for antibodies within the lupus anticoagulant spectrum which may contribute to clotting.

Components:

DRVVT PANEL, LA HEX DIFF, PTT-LA sens., PLATELET NEUTRALIZING, PROTHROMBIN TIME (PT), MIXING STUDIES-APTT, P.T.T.

ORDERING:

Test Code:

5817-2

Turnaround Time:

7 DAYS

Preferred Specimen:

3 mL Aliquot Plasma-Citrated-Blue Top

Collection:

Container	Qty	Temp	Stability
Aliquot Plasma-Citrated-Blue Top	5	STRICT Frozen	30 DAYS

Collection Instructions:

ALQC: Collect full blue-top (citrated) tube. Centrifuge Blue-top at high speed for 15 minutes. Transfer plasma into plastic transfer tube. Label with date/time collected, PLASMA and patient's name.

Storage Transport Instructions:

Custom Instruction: Collect 3 full blue-top (citrated) tubes. Centrifuge Blue-tops at high speed for 15 minutes. Transfer plasma into 5 plastic transfer tubes. Label with date/time collected, PLASMA, patient's name and FREEZE.
Storage/Transport Instruction: MUST BE SUBMITTED FROZEN

Specimen Comment:

Screen is for Elevated PTT. Please submit 5 tubes of citrated plasma aliquots.