TH53 : OnkoSight Advanced GYN Tumor NGS

INFORMATION:

Alternate Name:

Advanced GYN Tumor NGS

Methodology:

Genotyping by Next Generation Sequencing

Clinical Utility:

50 gene panel which includes Tumor mutation burden (TMB) and microsatellite instability (MSI). List of 50 genes: AKT1 AR ATM BRAF BRCA1 BRCA2 BRIP1 CCNE1 CDH1 CDK12 CHEK1 CHEK2 EGFR EPCAM ERBB2 ERBB3 ESR1 FANCA FANCC FANCL FGFR1 FGFR2 FOXA1 KRAS MLH1 MRE11A MSH2 MSH6 MUTYH MYC NBN NF1 PALB2 PIK3CA PMS2 POLE PTEN RAD50 RAD51B RAD51C RAD51D RAD54L RB1 RECQL4 SLX4 SMARCA4 TBX3 TERT TP53 XRCC2

ORDERING:

Test Code:

TH53-2

Turnaround Time:

10 DAYS

Preferred Specimen:

Formalin-fixed, Paraffin-embedded Tissue

Collection:

Container	Qty	Temp	Stability
Formalin-fixed, Paraffin-embedded Tissue	1	Room Temp

Collection Instructions:

BLK: This comes in block form from client with surgical number imprint.

Storage Transport Instructions:

CUSTOM INSTRUCTIONS: This comes in block form from client with surgical imprint.
10-15 unstained slides at 5 microns (tumor content>10%) with H&E, Shavings (if tumor content>40%) with H&E. If sending DNA- Please call Client Services.
Storage/Transport Instruction: Specimen can be either RT or refrigerated
Ship with cold pack during warm weather.
Extracted DNA is acceptable, providing that the isolation of nucleic acid occurs in a CLIA-certified laboratory or a laboratory meeting equivalent requirements as determined by CMS and/or the CAP.

Specimen Comment:

TQ30 OnkoHRD is available only to Non-NY clients as an add-on test and must be ordered concurrently or within 30 days of the sample receipt date

Alternative Specimen:

Eppendorf tube, Shavings, Unstained Slide