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TN04 : Cardio IQ Insulin Resistance Panel with Score

INFORMATION:

Alternate Name:
Cardio IQ Insulin Resis
Methodology:
Liquid Chromatography Tandem Mass Spectrometry
Clinical Utility:
The determination of insulin in serum is primarily used for the diagnosis of glycemic disorders in diabetic and pre-diabetic patients in the assessment of insulin resistant syndromes. Insulin is synthesized by the pancreatic beta cell as a precursor, proinsulin. Proinsulin is processed to insulin and C-peptide, a contiguous peptide between the insulin A and B chains, as it passes through the cell. The C-peptide in the proinsulin ensures correct folding and processing of proinsulin as it passes through the cell. Both insulin and C-peptide are released together from the beta cells in response to increased glucose levels. Because of differences in half-life and hepatic clearance, peripheral blood levels of C-peptide and insulin are no longer equimolar but remain highly correlated. A steady-state plasma glucose test in individuals undergoing an insulin suppression test to assess insulin resistance found that the combination of insulin and C-peptide was a better indicator of insulin resistance than either one individually.

ORDERING:

Test Code:
TN04-2
Turnaround Time:
8 DAYS
Preferred Specimen:
0.5 mL SST Tube
Collection:
Container Qty Temp Stability
SST Tube 1 Refrigerate 7 DAYS
Collection Instructions:
SST: Fill tube, invert gently 5 times, label with patient name, let stand for minimum of 30 minutes, maximum of 1 hr, spin for 10-15 minutes
Storage Transport Instructions:
Collect blood samples observing routine precautions for venipuncture. Allow serum samples to clot completely before centrifugation.
Alternative Specimen:
Aliquot Tube-Serum

Billing:

CPT Codes:
83525 x 1, 84681 x 1

CPT Code Disclaimer

CPT codes provided are for informational purposes only. Accuracy of CPT presented should be validated prior to consideration for billing.
CPT coding is the sole responsibility of the billing party. Please direct any questions regarding CPT coding to the payer being billed.