Back to Test DirectoryTP00 : OnkoSight Advanced NGS MYD88 and CXCR4 Panel
INFORMATION:
Alternate Name:
OSA MYD88 & CXCR4
Methodology:
Genotyping by Next Generation Sequencing
Clinical Utility:
p.Leu265Pro (L265P) mutation in the MYD88 gene is found in approximately 90% of Waldenstrom macroglobulinemia and lymphoplasmacytic lymphoma (LPL).
CXCR4 gene is rare but is indicated for WHIM (Warts, Hypogammaglobulinemia, Infection and Myelokathexis) syndrome.
Gene:
MYD88
CXCR4
ORDERING:
Test Code:
TP00-6
Turnaround Time:
10 DAYS
Preferred Specimen:
Bone Marrow - Lavender Top
Collection:
| Container | Qty | Temp | Stability |
|---|---|---|---|
| Bone Marrow - Lavender Top | 1 | Room Temp |
Collection Instructions:
BML: Place bone marrow into tube, label with patient's name
Storage Transport Instructions:
BML/BMG: Place bone marrow into tube, label with patient's name and date of birth.
GPB/LPB: Place peripheral blood into tube, label with patient's name and date of birth.
If submitting Bone Marrow or Peripheral Blood, 5 ml is required. Alternative specimen: Extracted DNA is acceptable, providing that the isolation of nucleic acid occurs in a CLIA-certified laboratory or a laboratory meeting equivalent requirements as determined by CMS and/or the CAP.
Storage/Transport Instruction: Specimen can be sent either RT or refrigerated.
BLK: This comes in block form from client with surgical number imprint.
Custom Instruction: 10-15 unstained slides at 5 microns (tumor content>10%) with H&E, stable for 30 days.
Specimen can be sent either room temperature or refrigerated. Ship with cold pack during warm weather.
GPB/LPB: Place peripheral blood into tube, label with patient's name and date of birth.
If submitting Bone Marrow or Peripheral Blood, 5 ml is required. Alternative specimen: Extracted DNA is acceptable, providing that the isolation of nucleic acid occurs in a CLIA-certified laboratory or a laboratory meeting equivalent requirements as determined by CMS and/or the CAP.
Storage/Transport Instruction: Specimen can be sent either RT or refrigerated.
BLK: This comes in block form from client with surgical number imprint.
Custom Instruction: 10-15 unstained slides at 5 microns (tumor content>10%) with H&E, stable for 30 days.
Specimen can be sent either room temperature or refrigerated. Ship with cold pack during warm weather.
Alternative Specimen:
Bone Marrow - Green Top, Peripheral Blood - Green Top, Peripheral Blood - Lavender Top, Formalin-fixed, Paraffin-embedded Tissue, Eppendorf tube
Billing:
CPT Codes:
81305 x 1, 81479 x 1
CPT Code Disclaimer
CPT codes provided are for informational purposes only. Accuracy of CPT presented should be validated prior to consideration for billing.
CPT coding is the sole responsibility of the billing party. Please direct any questions regarding CPT coding to the payer being billed.
